Comparison of diabetic nephropathy between male and female eNOS−/− db/db mice

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Role of Endothelial Nitric Oxide Synthase in Diabetic Nephropathy: Lessons from Diabetic eNOS Knockout Mice

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease in many countries. The animal models that recapitulate human DN undoubtedly facilitate our understanding of this disease and promote the development of new diagnostic markers and therapeutic interventions. Based on the clinical evidence showing the association of eNOS dysfunction with advanced DN, we and others have creat...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Renal Physiology

سال: 2019

ISSN: 1931-857X,1522-1466

DOI: 10.1152/ajprenal.00023.2019